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MDM2SNP309 andTP53R72P associated with severe and febrile neutropenia in breast cancer patients treated with 5-FU/epirubicin/cyclophosphamide

✍ Scribed by Masatsugu Okishiro; Seung Jin Kim; Ryo Tsunashima; Takahiro Nakayama; Kenzo Shimazu; Atsushi Shimomura; Naomi Maruyama; Yasuhiro Tamaki; Shinzaburo Noguchi


Book ID
113062274
Publisher
Springer US
Year
2011
Tongue
English
Weight
281 KB
Volume
132
Category
Article
ISSN
0167-6806

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Granisetron, a potent and selective 5-hydroxytryptamine receptor (5-HT3) antagonist was reported to be an effective antiemetic agent both in animal studies and in patients given highly emetogenic chemotherapy. A sample of 43 patients with breast cancer was accrued from September to November 1992 in