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Genetic mapping of the mouse topoisomerase IIα gene to Chromosome 11

✍ Scribed by Stephen F. Kingsmore; Chih-Min Tang; Cheng-Kai Lo; Cho-Fat Hui; Jaulang Hwang; Michael F. Seldin

Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
136 KB
Volume
4
Category
Article
ISSN
0938-8990

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DNA topoisomerase I is a highly conserved and ubiquitously expressed protein of eukaryotes. D N A topoisomerase I is indispensable in DNA transcription and replication and in the maintenance of genomic stability, relaxing D N A s u p e r c o i l s , and s u p p r e s s i n g c h r o m o s o m a l re