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Genetic distance in sequence space of evolving populations

✍ Scribed by Elisangela Ferretti Manffra; Holger Kantz; Mario Ragwitz

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 183 KB
Volume: 8
Category: Article
ISSN: 1076-2787
DOI: 10.1002/cplx.10088

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A genome‐based measure for the distance between two populations is introduced. It fulfills the triangular inequality and can be easily computed, when the genetic sequences of a large number of individuals in two different populations are given. We use this distance for a study of mutating populations evolving under selective pressure, which are “living” on a computer. As a particular result, we find that evolution is diffusive. We include a comparison of our novel concept and the notion of genomic complexity of populations introduced by Adami et al. (Adami, C.; Ofria, C.; Collier, T.C. Evolution of biological complexity. Proc Natl Acad Sci USA 2000, 97, 4463–4468.) © 2003 Wiley Periodicals, Inc.

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