The mean survival time of these animals was significantly longer than that of kd tumor-susceptihle mice..
Genetic control of responsiveness to the tumor-associated transplantation antigen of a chemically induced murine fibrosarcoma
✍ Scribed by Giorgio Parmiani
- Publisher
- Springer-Verlag
- Year
- 1978
- Tongue
- English
- Weight
- 315 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0093-7711
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A tumor rejection antigen (TATA), obtained from the cytosol of a BALB/c mKSA sarcoma induced by SV40 virus, has been partially purified. This partially purified antigen is strikingly immunogenic against mKSA, providing more than 90% inhibition of growth at levels of 10-30 pg. This antigen preparatio
## Abstract We have previously shown that the methyl‐cholanthrene‐induced BALB/c fibrosarcoma C‐1 syngeneically transplanted __in vivo__ expressed, in addition to its original H‐2^d^ and tumor‐associated transplantation antigens, also the foreign H‐2K^k^ 23, 1, 5, 11, 25 specificities. In the prese
## Abstract Soluble tumor antigens were prepared from chemically‐induced rat fibrosarcoma KMT‐17 cells by various methods [Na‐deoxycholate (DOC), 3 M‐KCI extraction, and crude membrane preparations by mechanical disruption]. Soluble tumor antigens prepared by DOC extraction (DOC‐STA) could be detec
## Abstract The tumor‐associated transplantation antigen (TATA), alien H‐2^k^ antigens and normal H‐2^d^ antigens expressed on a methylcholanthrene‐induced tumor were monitored during gel filtration and lectin affinity chromatography of detergent‐solubilized tumor‐cell membranes. TATA was resolved