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Genetic analysis workshop III: Use of multidimensional scaling in chromosome mapping

✍ Scribed by J. Donald; E. Sturt; G. Der; K. McCusker

Publisher: John Wiley and Sons
Year: 1985
Tongue: English
Weight: 142 KB
Volume: 2
Category: Article
ISSN: 0741-0395
DOI: 10.1002/gepi.1370020216

No coin nor oath required. For personal study only.

✦ Synopsis

Two-point methods were used throughout. Male and female lod scores were calculated using LIPED. Edwards' programs, ZLODS and OBM, were used for joint analysis of the lod scores. ZLODS estimates recombination fractions. OBM calculates the likelihood and estimates the map distances for a given ordering of loci. Since OBM will only analyze a specified ordering, multidimensional scaling was used as a general method for establishing linkage groups and likely orderings within them.

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