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Genetic analysis of a breast-ovarian cancer gene (BRCA1) on chromosome 17q

✍ Scribed by U. Hamann; J. Chang-Claude; U. Vogel; T. Bishop; H. Becher


Book ID
119106240
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
91 KB
Volume
77
Category
Article
ISSN
0165-4608

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BRCA1 gene mutation and loss of heterozy
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The tumor suppressor gene BRCA1 on chromosome 17q21 has been characterized and shown to be mutated in patients with familial breast and ovarian cancer. Several studies examined the relatives of women with breast cancer and noted an association with ovarian and prostate cancer. This study investigate