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BRCA1 and BRCA1 Genes and Inherited Breast and/or Ovarian Cancer: Benefits of Genetic Testing

โœ Scribed by Kumaravel Somasundaram


Book ID
107688955
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
126 KB
Volume
1
Category
Article
ISSN
0975-7651

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A total of 283 epithelial ovarian cancer families from the United Kingdom (UK) and the United States (US) were screened for coding sequence changes and large genomic alterations (rearrangements and deletions) in the BRCA1 and BRCA2 genes. Deleterious BRCA1 mutations were identified in 104 families (