Diffusely infiltrating low-grade astrocytomas (WHO grade II) have an intrinsic tendency for progression to anaplastic astrocytoma (WHO grade III) and glioblastoma (WHO grade IV). This change is due to the sequential acquisition of genetic alterations, several of which have recently been identified.
Genetic alterations of the NRP/B gene are associated with human brain tumors
β Scribed by Liang, Xing-Qun; Avraham, Hava Karsenty; Jiang, Shuxian; Avraham, Shalom
- Book ID
- 110068845
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 252 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0950-9232
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