Generation of α-hydroxyaldehydic compounds in the course of lipid peroxidation
✍ Scribed by Angelika Loidl-Stahlhofen; Kerstin Hannemann; G. Spiteller
- Book ID
- 115741328
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 853 KB
- Volume
- 1213
- Category
- Article
- ISSN
- 0005-2760
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📜 SIMILAR VOLUMES
## Abstract A method to detect short‐chain α‐hydroxyaldehydes in mammalian tissues is described. Aldehydes or their masked precursor molecules are converted into dithiolane derivatives. These are separated by thin‐layer chromatography and registered by multiple ion monitoring after trimethylsilylat
Pentafluorbenzyloxime derivatization allows fast, gentle and unambiguous identification of ~-hydroxyaldehydic lipid peroxidation products via GC/MS in biological material. Even 1.5 g of a bovine liver sample is sufficient to detect short-chain 2-hydroxyalkanales resulting from cleavage reactions of