The iron-mediated reactivity of various dispiro-1,2,4-trioxolanes was determined by automated kinetic analysis under standard reaction conditions. The active antimalarial compounds underwent peroxide bond cleavage by Fe(II) resulting in products indicative of carbon-centered radical formation. The r
β¦ LIBER β¦
Generation of radicals and antimalarial activity of dispiro-1,2,4-trioxolanes
β Scribed by Denisov, E. T.; Denisova, T. G.
- Book ID
- 120281819
- Publisher
- International Academic Publishing Co (Nauka/Interperiodica)
- Year
- 2012
- Tongue
- English
- Weight
- 396 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0036-0244
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