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Generation of Hydroxyl Radicals by the Antiviral Compound Phosphonoformic Acid (Foscarnet)

✍ Scribed by Lindqvist, Christer ;Nordström, Tommy

Book ID: 111262663
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 218 KB
Volume: 89
Category: Article
ISSN: 0901-9928
DOI: 10.1111/j.1600-0773.2001.890108.x

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## Abstract Reactive oxygen species, probably hydroxyl radicals (OH·), have been suggested to be generated during arachidonic acid (AA) metabolism and, once released, these species can modify the rate and extent of various reactions involved in AA metabolism. We have studied this phenomenon in wash