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The generation of hydroxyl radicals following superoxide production by neutrophil NADPH oxidase

✍ Scribed by J.V. Bannister; P. Bellavite; A. Davoli; P.J. Thornalley; F. Rossi

Book ID
115913674
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
244 KB
Volume
150
Category
Article
ISSN
0014-5793

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## Abstract Superoxide is produced by a NADPH oxidase of phagocytic cells and contributes to their microbicidal activities. The oxidase is activated when receptors in the neutrophil plasma membrane bind to the target microbe. These receptors recognise antibodies and complement fragments which coat