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Generation of activated and antigen-specific T cells with cytotoxic activity after co-culture with dendritic cells

✍ Scribed by Angela Märten, Tim Greten, Carsten Ziske, Sabine Renoth, Björn Schöttker, Peter Buttgereit, Frank Schakowski, Alexander von Rücker, Tilman Sauerbruch, Ingo G. Schmidt-Wolf


Book ID
105966513
Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
177 KB
Volume
51
Category
Article
ISSN
0340-7004

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## Abstract ## Background Genetic modification of human monocyte‐derived dendritic cells (DC) with cDNA sequences encoding tumor‐associated antigens (TAA) is a promising strategy for cancer immunotherapy. The present study aimed to develop a nonviral gene transfer method based on the use of the ca