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General Synthesis and Physicochemical Characterisation of a Series of Peptide-Mimic Lysine-Based Amino-Functionalised Lipids

✍ Scribed by Wölk, Christian; Drescher, Simon; Meister, Annette; Blume, Alfred; Langner, Andreas; Dobner, Bodo


Book ID
121872575
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
867 KB
Volume
19
Category
Article
ISSN
0947-6539

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✍ George Kokotos; JoséM. Padrón; Caterina Noula; William A. Gibbons; Victor S. Mar 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 620 KB

A general methodology for the synthesis of saturated lipidic amino acids based on the oxidative cleavage of amino diols obtained by the regioselective opening of enantiomerically enriched 2,3-epoxy alcohols is described. The method opens the way to the synthesis of the enantiomers of lipidic 2-amino