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General Route to a New Class of Homochiral Azetidine-Derived 1,2-Diamines.

โœ Scribed by Francois Couty; Gwilherm Evano; Damien Prim; Jerome Marrot


Book ID
101967254
Publisher
John Wiley and Sons
Year
2004
Weight
33 KB
Volume
35
Category
Article
ISSN
0931-7597

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General Route to a New Class of Homochir
โœ Franรงois Couty; Gwilherm Evano; Damien Prim; Jรฉrome Marrot ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 131 KB

## Abstract A short access to novel azetidineโ€derived __anti__โ€1,2โ€diamines starting from easily accessible 2โ€cyanoazetidines has been developed. A oneโ€pot sequence, including a nucleophilic addition and reduction of the resulting imine, allows for a diastereoselective synthesis of variously substi