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ChemInform Abstract: Lipase-Catalyzed Transesterification as a Practical Route to Homochiral Acyclic anti-1,2-Diols. A New Synthesis of (+)- and (-)- endo-Brevicomin.

โœ Scribed by M.-J. KIM; G.-B. CHOI; J.-Y. KIM; H.-J. KIM


Book ID
112023691
Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
26
Category
Article
ISSN
0931-7597

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Lipase-catalyzed transesterification as
โœ Donghyun Lee; Mahn-Joo Kim ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 194 KB

syn-2,3-Dihydoxy-3-phenyl-propanoic acid methyl ester (la) and its simple derivatives (lb-e) are efficiently resolved in LPS-catalyzed transesterification, leading to the synthesis of the taxol side chain and analogs from both resolved enantiomers.