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Derivatives of 1,2-diazetine-1,2-dioxide: A new class of nitric oxide generators exhibiting vasodilator activity

โœ Scribed by G. Ya. Shvarts; N. B. Grigor'ev; I. S. Severina; I. K. Ryaposova; A. S. Lapitskaya; L. B. Volodarskii; A. Ya. Tikhonov; I. F. Kurbnikova; D. G. Mazhukin; V. G. Granik


Book ID
112713766
Publisher
Springer
Year
1994
Tongue
English
Weight
423 KB
Volume
28
Category
Article
ISSN
0091-150X

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## Abstract A short access to novel azetidineโ€derived __anti__โ€1,2โ€diamines starting from easily accessible 2โ€cyanoazetidines has been developed. A oneโ€pot sequence, including a nucleophilic addition and reduction of the resulting imine, allows for a diastereoselective synthesis of variously substi