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Gene Therapy for Gliomas: Molecular Targets, Adenoviral Vectors, and Oncolytic Adenoviruses

✍ Scribed by Ramon Alemany; Candelaria Gomez-Manzano; Cristina Balagué; W.K. Alfred Yung; David T. Curiel; Athanassios P. Kyritsis; Juan Fueyo

Book ID
115603429
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
95 KB
Volume
252
Category
Article
ISSN
0014-4827

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## Abstract ## Background Despite attempts to develop efficient viral‐based gene transfer therapies for the treatment of malignant tumors, only limited progress has been made to improve the efficacy of this approach. As an alternative, the use of replicating oncolytic adenoviruses with and without