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CD46 Represents a Target for Adenoviral Gene Therapy of Malignant Glioma

✍ Scribed by Ulasov, Ilya V.; Tyler, Matthew A.; Zheng, Sophy; Han, Yu; Lesniak, Maciej S.

Book ID: 123607731
Publisher: Mary Ann Liebert
Year: 2006
Tongue: English
Weight: 276 KB
Volume: 17
Category: Article
ISSN: 1043-0342
DOI: 10.1089/hum.2006.17.556

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## Abstract ## Background Malignant glioma has a dismal prognosis. It was previously shown that glioma cells are efficiently killed when they express a gene coding for a hyperfusogenic mutant of the gibbon ape leukemia virus envelope glycoprotein (GALV.fus). However, production of viral vectors ex