Recombinant Baculovirus Containing the Diphtheria Toxin A Gene for Malignant Glioma Therapy

Investigation of a plasmid containing a

Investigation of a plasmid containing a novel immunotoxin VEGF165-PE38 gene for antiangiogenic therapy in a malignant glioma model

✍ Chang-chen Hu; Hong-ming Ji; Sheng-li Chen; Han-wei Zhang; Bin-quan Wang; Li-yua 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 639 KB

## Abstract Inhibition of tumor neovascularization has profound effects on the growth of solid tumors. Our previous studies have shown the effect of VEGF165‐PE38 recombinant immunotoxin on proliferation and apoptosis in human umbilical vein endothelial cells __in vitro__. In this study, we explored