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Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers

✍ Scribed by Yun, Jiyeon; Song, Sang-Hyun; Park, Jinah; Kim, Hwang-Phill; Yoon, Young-Kwang; Lee, Kyung-Hun; Han, Sae-Won; Oh, Do-Youn; Im, Seock-Ah; Bang, Yung-Jue; Kim, Tae-You

Book ID
118033119
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
570 KB
Volume
92
Category
Article
ISSN
0023-6837

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## Abstract Secreted frizzled‐related protein 2 (__sFRP2__) is a negative modulator of the Wingless‐type (Wnt) signaling pathway, and shown to be inactivated in renal cell carcinoma (RCC). However, the molecular mechanism of silencing of __sFRP2__ is not fully understood. Our study was designed to