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Gene regulation by MAP kinase cascades

โœ Scribed by Berthe Katrine Fiil; Klaus Petersen; Morten Petersen; John Mundy


Book ID
113843013
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
320 KB
Volume
12
Category
Article
ISSN
1369-5266

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Some protein kinases operate in more than one mitogen-activated protein-kinase (MAPK) cascade. We here address the question whether specificity of the cascades necessitates physical sequestration of these "promiscuous" kinases (e.g. by binding to scaffolds). A model is constructed, in which two MAPK