Gene for apolipoprotein CII is on human chromosome 19
β Scribed by M. Jeanpierre; D. Weil; M. C. Hors-Cayla; R. Williamson; C. Junien; S. E. Humphries
- Book ID
- 112557867
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 414 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1572-9931
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We have demonstrated close linkage between the genes for apolipoprotein E (apoE) and apolipoprotein CII (apoCII). Families segregating for apoE protein variants were screened for a DNA restriction fragment length polymorphism close to the apoCII gene by using an apoCII cDNA clone. The maximum lod sc
We have isolated a cDNA clone for apolipoprotein CI and a genomic clone for apolipoprotein E, and by hybridisation and mapping experiments found the gene for apoCI to be located on the genomic apoE clone. The distance between the loci was 4.3 kb.