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Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma

โœ Scribed by Fertig, Elana J; Ren, Qing; Cheng, Haixia; Hatakeyama, Hiromitsu; Dicker, Adam P; Rodeck, Ulrich; Considine, Michael; Ochs, Michael F; Chung, Christine H


Book ID
119894752
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
289 KB
Volume
13
Category
Article
ISSN
1471-2164

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## Abstract Noninvasive imaging of the epidermal growth factor receptor (EGFR) in headโ€andโ€neck squamous cell carcinoma could be of value to select patients for EGFRโ€targeted therapy. We assessed dose optimization of ^111^Indiumโ€DTPAโ€cetuximab (^111^Inโ€cetuximab) for EGFR imaging in a headโ€andโ€neck