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Gene-expression profiling and cancer of an unknown primary origin

✍ Scribed by Jame Abraham


Book ID
118628244
Publisher
Frontline Medical Communications, Inc.
Year
2008
Tongue
English
Weight
59 KB
Volume
5
Category
Article
ISSN
1548-5315

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Lung cancer is a highly aggressive neoplasm with 85% mortality. To identify new tumor-associated genes, we compared the expression profile of a primary metastasizing adenocarcinoma with normal airway epithelial cells. Two cDNA libraries of up-and downregulated genes were generated, comprising 253 an