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Gene expression pattern of the epidermal growth factor receptor family and LRIG1 in renal cell carcinoma

✍ Scribed by Marcus Thomasson, Håkan Hedman, Börje Ljungberg, Roger Henriksson

Book ID
119912621
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
202 KB
Volume
5
Category
Article
ISSN
1756-0500

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We examined 22 cases of renal-cell carcinoma (RCC) for structural alterations of the epidermal growth factor receptor (ECFR) gene and found gene amplification in one case of high-stag+high-grade RCC. Dot blot analysis of the total RNA from tumorous and normal kidney tissues revealed overexpression o