Gene amplification in V79 Chinese hamster cells
โ Scribed by L. Ottaggio; S. Bonatti; F. Tosetti; M. Miele; P. Degan; G. Montagnoli; R. Randazzo; C. Agnese; P. Cavolina; A. Di Leonardo; A. Abbondandolo
- Book ID
- 113193251
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 81 KB
- Volume
- 181
- Category
- Article
- ISSN
- 0027-5107
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To investigate the induction of gene amplification by a transient inhibition of DNA synthesis, V79-AP4 Chinese hamster cells were treated with 1-beta-D-arabinofuranosylcytosine (araC). At given intervals after the treatment, the frequency of N-(phosphonacetyl)-L-aspartate (PALA)-resistant colony-for