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Gene amplification in human neuroblastomas: Basic mechanisms and clinical implications

✍ Scribed by Garrett M. Brodeur; Robert C. Seeger


Book ID
119103346
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
700 KB
Volume
19
Category
Article
ISSN
0165-4608

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Neuron-specific src mRNA, which is expressed in human brain tissue by alternative splicing, is associated with neural differentiation. Neuronal c-srcN I expression may be associated with the ability of neuroblastomas to mature; furthermore. c-srcN2 mRNA is induced in chemically differentiated neumbk