𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Clinical implications of oncogene activation in human neuroblastomas

✍ Scribed by Garrett M. Brodeur; Robert C. Seeger; Harland Sather; Andree Dalton; Stuart E. Siegel; Kwan Y. Wong; Denman Hammond


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
494 KB
Volume
58
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Amplification of oncogenes in human canc
✍ Manfred Schwab πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 369 KB πŸ‘ 2 views

Gene amplification refers to a genomic change that results in an increased dosage of the gene(s) affected. Amplification represents one of the major molecular pathways through which the oncogenic potential of proto-oncogenes is activated during tumorigenesis. The architecture of amplified genomic st

Expression of theRET proto-oncogene in h
✍ AttiοΏ½-Bitach, Tania; Abitbol, Marc; GοΏ½rard, Marion; Delezoide, Anne-Lise; AugοΏ½, πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 71 KB πŸ‘ 2 views

The patterns of RET proto-oncogene expression in mouse, rat, and chicken and the anomalies observed in targeted RET mutants suggest that RET plays a major role in development of mouse enteric nervous system and in kidney organogenesis. Here, we report on in situ hybridization studies describing the

Promiscuous translocations of chromosome
✍ Maria Lastowska; Paul Roberts; Andrew D. J. Pearson; Ian Lewis; John Wolstenholm πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 187 KB πŸ‘ 2 views

Deletions of chromosome arm 1p and amplification of the MYCN oncogene are well-recognized genetic changes in neuroblastoma cells. Technical difficulties in cytogenetic analysis of this tumour have hampered the recognition of other recurring abnormalities, but recent use of molecular cytogenetic tech

Mutational analysis of the p16 gene in h
✍ Javier S. Castresana; Lourdes GΓ³mez; PurificaciΓ³n GarcΓ­a-Miguel; Antonio QueizΓ‘n πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 185 KB πŸ‘ 2 views

Neuroblastoma is one of the most frequent tumors in infancy. We analyzed 26 neuroblastomas, two ganglioneuromas, and a neuroblastoma metastasis for mutations and homozygous deletions of the p16 (or MTS1 or CDKN2) gene by means of the polymerase chain reaction (PCR) in combination with the single-str

Incidence of ras oncogene activation in
✍ Maria Li Lung; Maria Wong; Wah Kit Lam; Kam Sking Lau; Susan Kwan; Kin-Hang Fu; πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 399 KB πŸ‘ 1 views

## Background: In hong kong, lung carcinomas contribute to the majority of cancer deaths among chinese. point mutational activation of ras oncogenes has been observed in several populations. the incidence of these mutations in hong kong lung carcinomas was investigated. ## Methods: Lung resection

Optical-thermal simulation of human tons
✍ Rahul K. Shah; Babak Nemati; Lihong V. Wang; Mark S. Volk; Stanley M. Shapshay πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 121 KB πŸ‘ 1 views

## Background and objective: Mucosa intact laser tonsillar ablation is an alternative to conventional tonsillectomy. the efficacy of this procedure was demonstrated in canines, but establishing the safety of irradiating human tonsils is paramount. ## Study design/materials and methods: An optical