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Gene amplification in cancer

โœ Scribed by Donna G. Albertson


Book ID
113932770
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
499 KB
Volume
22
Category
Article
ISSN
0168-9525

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Gene amplification is a model of proto-oncogene alterations occasionally observed in human tumors. This amplification can, in some cases, have prognostic value (N-myc in neuroblastoma, c-erbB2 and int-2 in breast cancer, etc.). Amplifications of the proto-oncogenes c-myc, c-erbB2 and int-2 have not