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Gene amplification and p53 expression in 123 bone and soft tissue sarcomas (BSTS)

✍ Scribed by A. Peydró-Mellquist; E. Röijer; P. Söderkvist; H. Sjögren; J.M. Meis-Kindblom; L.G. Kindblom; G. Stenman

Book ID
114136551
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
91 KB
Volume
91
Category
Article
ISSN
0165-4608

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The aim of this study is to address the role of mdm-2-gene amplification in the tumorigenesis of uterine sarcomas. Differential PCR with DNA from formalin-fixed paraffin-embedded specimens was employed in 12 patients with uterine sarcomas. We detected mdm-2-gene amplification in 4 out of 12 uterine