Clinical relevance of pRb and p53 Co-overexpression in soft tissue sarcomas
✍ Scribed by Peter Würl; Axel Meye; Christine Lautenschläger; Hannelore Schmidt; Matthias Bache; Holger Kalthoff; Manfred Schönfelder; Friedrich-Wilhelm Rath; Helge Taubert
- Book ID
- 117469401
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 102 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0304-3835
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## Abstract ## BACKGROUND __p53__ is the most commonly mutated gene in cancer, including soft tissue sarcoma (STS). The authors characterized p53 alterations (protein accumulation and gene mutation) in STS to evaluate possible associations with patient outcomes. ## METHODS Thirty‐one STS specime
Background and Objectives: Soft-tissue sarcomas (STS) represent a diverse histologic group of malignancies at risk for local and distant failure. We studied the impact of late (5 or more years) vs. early recurrence (less than 5 years) on subsequent outcome. Methods: Four hundred sixty-eight patients