Amplification of the mdm-2 gene and p53
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Akihiko Seki; Junichi Kodama; Yasunari Miyagi; Shigehito Kamimura; Mitsuo Yoshin
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Article
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1997
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John Wiley and Sons
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French
β 142 KB
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The aim of this study is to address the role of mdm-2-gene amplification in the tumorigenesis of uterine sarcomas. Differential PCR with DNA from formalin-fixed paraffin-embedded specimens was employed in 12 patients with uterine sarcomas. We detected mdm-2-gene amplification in 4 out of 12 uterine