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Gene Amplification and Increased Expression of the Reduced Folate Carrier in Transport Elevated K562 Cells

โœ Scribed by So C Wong; Long Zhang; Susan A Proefke; Bharati Hukku; Larry H Matherly

Book ID
113994033
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
457 KB
Volume
55
Category
Article
ISSN
0006-2952

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โœ Giuseppe Corona; Franca Giannini; Martina Fabris; Giuseppe Toffoli; Mauro Boiocc ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 166 KB ๐Ÿ‘ 2 views

Folate receptor-โฃ (FR-โฃ) is generally over-expressed in non-mucinous human ovarian carcinomas. The meaning of FR-โฃ over-expression and its role in the 5-methyltetrahydrofolic acid (N 5 -CH 3 -H 4 PteGlu) transport in such tumors is not clear, especially compared with the reduced folate carrier (RFC)