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GD1b-specific antibodies may bind to complex of GQ1b and GM1, causing ataxia

✍ Scribed by Nobuhiro Yuki,Yuki Fukami,Chiaki Yanaka,Saiko Koike…

Book ID
125347044
Publisher
Springer
Year
2014
Tongue
English
Weight
586 KB
Volume
261
Category
Article
ISSN
0340-5354

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Binding of antibodies against GM1 and GD
Binding of antibodies against GM1 and GD1b in human peripheral nerve
✍ Susumu Kusunoki; Hiromi Mashiko; Noriko Mochizuki; Atsuro Chiba; Masanobu Arita; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 532 KB

Human dorsal root ganglia (DRG), and ventral and dorsal roots were immunostained with rabbit antibodies recognizing GM1, GD1b, or both. Sera from rabbits immunized with GM1 or GD1b were separated in affinity columns into three fractions: Rab1, Rab2, and Rab3. Rab1 recognized only GM1, and Rab2 only