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Ganglioside accumulation in cultured skin fibroblasts from gangliosidosis patients

โœ Scribed by Raju K. Pullarkat; Henry Reha; Nicholas G. Beratis


Book ID
118315165
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
645 KB
Volume
92
Category
Article
ISSN
0006-291X

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GM1-gangliosidosis: Accumulation of gang
โœ Yoshiyuki Suzuki; Norimasa Nakamura; Kazuko Fukuoka ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer ๐ŸŒ English โš– 270 KB

Uptake of radioactivity from 14C-galactose into gangliosides by cultured skin fibroblasts was studied. GM3 was the major ganglioside in control human fibroblasts. An increase of GM1 was demonstrated in GM1-gangliosidosis fibroblasts. The degree of GM1 accumulation was correlated with the clinical ty