GM1-gangliosidosis: Accumulation of gang
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Yoshiyuki Suzuki; Norimasa Nakamura; Kazuko Fukuoka
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Article
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1978
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Springer
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English
โ 270 KB
Uptake of radioactivity from 14C-galactose into gangliosides by cultured skin fibroblasts was studied. GM3 was the major ganglioside in control human fibroblasts. An increase of GM1 was demonstrated in GM1-gangliosidosis fibroblasts. The degree of GM1 accumulation was correlated with the clinical ty