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Galectin-3 and cyclin D1 expression in non-small cell lung cancer

✍ Scribed by Monika Kosacka; Paweł Piesiak; Aneta Kowal; Marcin Gołecki; Renata Jankowska

Book ID
119913673
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
324 KB
Volume
30
Category
Article
ISSN
1756-9966

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Among the major regulators of the G 1 restriction point are cyclin D1 and the retinoblastoma gene product (RB). In non-small cell lung cancer (NSCLC), the cyclin D1 gene is amplified/over-expressed in almost 50% of cases, and RB is inactivated in 6-32% of cases. It is of interest to evaluate concurr