Galactose-1-phosphate uridyl transferase in density-fractionated erythrocytes
β Scribed by Richard I. Kelley; Daniel M. Feinberg; Stanton Segal
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 697 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0340-6717
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π SIMILAR VOLUMES
The enzyme galactose-1-phosphate uridyl transferase (E.C.2.7.7.12), which has an important function in the metabolism of galactose, exists in multiple molecular forms. The different phenotypes are genetically determined. They can be distinguished according to their electrophoretic mobility. The enzy
The frequency of variants of galactose-1-phosphate uridyl transferase was determined among the nine Greek populations by studying a sample of 1570 unselected individuals. Average frequency of normal allele GALT=0.942, galactosemia gen GALTG=0.0021 and the Duarte variant gene GALTD=0.0548 were observ
## Abstract An improved isoelectric focusing (IEF) technique has been developed and used to detect the erythrocyte galactoseβ1βphosphate uridyl transferase isoenzymes. The normal enzyme was resolved by IEF in four bands with isoelectric points (pI) between 5.80 and 6.08. Numerous samples, classifie