Two molecular defects have been described in parathyroid adenomas: rearrangement and overexpression of the PRADllcyclin D I oncogene and allelic loss of chromosome I I DNA, often including the multiple endocrine neoplasia type I (MENI) putative tumor suppressor gene region. In an effort to identify
Gain of chromosome 3 and loss of 13q are frequent alterations in pituitary adenomas
✍ Scribed by Xing Fan; Anders Paetau; Yan Aalto; Matti Välimäki; Timo Sane; Antti Poranen; Javier S Castresana; Sakari Knuutila
- Book ID
- 114135071
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 118 KB
- Volume
- 128
- Category
- Article
- ISSN
- 0165-4608
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