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GAG and REV antisense oligodeoxynucleotides as inhibitors of HIV 1

โœ Scribed by D. Kinchington; S. Galpin; J. Jaroszewski; C. Subasinghe; K. Gosh; J.S. Cohen


Book ID
118392554
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
60 KB
Volume
15
Category
Article
ISSN
0166-3542

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The binding affinities of ten aminoglycosides with RRE IIB RNA have been determined. Neamine was found as the simplest consensus unit of aminoglycoside antibiotics that bind RRE IIB RNA tightly. Various aromatic ring-substituted neamines have been prepared and their binding with RRE IIB RNA was exam