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GABA, γ-hydroxybutyric acid, and neurological disease

✍ Scribed by C. Guin Ting Wong; Teodoro Bottiglieri; O. Carter Snead III

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
105 KB
Volume
54
Category
Article
ISSN
0364-5134

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g-Hydroxybutyric acid (GHB) is a drug of abuse. Literature studies showed that d-glucuronate acts as an oxidative stimulator of GHB metabolism following in vivo GHB tracer doses. The present proof-of-concept study investigates if d-glucuronate enhances GHB metabolism and inhibits blood-brain barrier