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GABA-Induced Potassium Channels in Cultured Neurons

✍ Scribed by L. S. Premkumar, S.-H. Chung and P. W. Gage


Book ID
123660614
Publisher
The Royal Society
Year
1990
Tongue
English
Weight
812 KB
Volume
241
Category
Article
ISSN
0080-4649

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We recorded whole-cell Cl- currents in cultured embryonic rat thalamic neurons by brief applications of GABA or the structural analogue muscimol. In 17 of 141 neurons (12%) the Cl- current persisted for a minute or more after the pipette was removed from the bath. Cl- current never persisted after m