Chloride currents were activated by a low concentration of GABA (0.5 microM) in neonatal rat hippocampal neurons cultured for up to 14 days. Currents elicited by 0.5 microM GABA in neurons, voltage-clamped using the whole-cell technique with pipettes containing 149 mM Cl-, reversed close to 0 mV whe
โฆ LIBER โฆ
Non-uniform distribution of GABA activated chloride channels in cultured cortical neurons
โ Scribed by Frosch, Matthew P.; Dichter, Marc A.
- Book ID
- 122948280
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 374 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Potassium channel dysfunction has been implicated in Alzheimer's disease (AD). In the present study, by using potassium channel blocker tetraethylammonium (TEA), we investigated the relationship between the enhancement of potassium currents and the alteration of apoptotic cascade in the