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Coupled Potassium Channels Induced by Arachidonic Acid in Cultured Neurons

✍ Scribed by Premkumar, L. S.; Gage, P. W.; Chung, S.-H.


Book ID
120141140
Publisher
The Royal Society
Year
1990
Tongue
English
Weight
885 KB
Volume
242
Category
Article
ISSN
0080-4649

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## Abstract A pathophysiological increase in free arachidonic acid (AA) is thought to regulate the channel‐mediated astrocytic swelling occurring in several brain injuries. We report that in cultured rat type‐1 cortical astrocytes, exposure to 10 ΞΌM AA activates an open rectifier K^+^ channel, whic