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G protein-coupled receptors: Crystallizing how agonists bind

✍ Scribed by Tse, Man Tsuey


Book ID
109951306
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
177 KB
Volume
10
Category
Article
ISSN
1474-1776

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## Abstract It has been recently established that G‐protein‐coupled receptors (GPCRs) can be constitutively active, i.e., they can be active in the absence of an agonist. This activity can be inhibited by so‐called inverse agonists. For a number of GPCRs, such inverse agonists have been developed a