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Agonist binding to G-protein coupled receptors

✍ Scribed by Philip G Strange


Book ID
110004722
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
89 KB
Volume
129
Category
Article
ISSN
0007-1188

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A model of non-exclusive binding of agon
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A modified concept of functioning of G-protein coupled receptors is presented, on the assumption that agonistic and antagonistic effects of drugs are related to their interaction with two separate receptor sites that exist simultaneously on a single receptor molecule and possess different ligand-spe