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Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors

✍ Scribed by Strange, P. G. (author)


Book ID
110009924
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
225 KB
Volume
153
Category
Article
ISSN
0007-1188

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A modified concept of functioning of G-protein coupled receptors is presented, on the assumption that agonistic and antagonistic effects of drugs are related to their interaction with two separate receptor sites that exist simultaneously on a single receptor molecule and possess different ligand-spe