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Fusion ofMLLandMSFin Adult De Novo Acute Myelomonocytic Leukemia (M4) with T(11;17)(Q23;Q25)

✍ Scribed by Koh Yamamoto; Fumi Shibata; Mitsuko Yamaguchi; Osamu Miura


Book ID
105675392
Publisher
Carden Jennings Publishing
Year
2002
Tongue
English
Weight
275 KB
Volume
75
Category
Article
ISSN
0925-5710

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Rearrangements of the MLL gene at chromosome 11q23 are uncommon in de novo myelodysplastic syndrome (MDS). Here, we describe molecular findings in a patient with multilineage dysplasia and t(11;17)(q23;q25) who responded to decitabine therapy. Fluorescent in situ hybridization (FISH) demonstrated re