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Coexistence of alternative MLL–SEPT9 fusion transcripts in an acute myeloid leukemia with t(11;17)(q23;q25)

✍ Scribed by Joana Santos; Nuno Cerveira; Cecília Correia; Susana Lisboa; Manuela Pinheiro; Lurdes Torres; Susana Bizarro; Joana Vieira; Luisa Viterbo; José M. Mariz; Manuel R. Teixeira

Book ID
113513664
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
605 KB
Volume
197
Category
Article
ISSN
0165-4608

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An MLL-SEPT9 fusion and t(11;17)(q23;q25
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✍ Lisa M. Baumann Kreuziger; Julie Cliff Porcher; Rhett P. Ketterling; David P. St 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 279 KB

Rearrangements of the MLL gene at chromosome 11q23 are uncommon in de novo myelodysplastic syndrome (MDS). Here, we describe molecular findings in a patient with multilineage dysplasia and t(11;17)(q23;q25) who responded to decitabine therapy. Fluorescent in situ hybridization (FISH) demonstrated re